The Rabbit Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to alkB homolog 3, alpha-ketoglutarate dependent dioxygenase, and ALKBH3. This antibody recognizes Human antigen. The Rabbit Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Antibody has been validated for the following applications: EIA, Immunoassay, and ELISA.
Description
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron